SYNHYDRID®

A New Standard in High Yield Reduction Chemistry

SAFE AND EFFECTIVE

The most effective organometallic reducing agent available

Synhydrid® is a highly versatile organometallic reducing agent that is safe and easy to handle. It is best known for a number of classic transformations and for its ability to replace more reactive and hazardous chemicals such as DIBAL & Lithium Aluminium Hydride (LAH).

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CAS No. 22722-98-1

Although Synhydrid® is represented as a single substance, it is actually a consistent thermodynamic-equilibrium mixture

The chemical name for Synhydrid® is Sodium bis(2-methoxyethoxy) aluminium hydride.

Synhydrid® is available as:

• 70% Synhydrid® (standard)

• 60% Synhydrid®

• Modified Synhydrid®

The product is also generically known as SDMA, Red-Al and is 70% solution in toluene.

The Synhydrid® Difference

Chematek understands that it is imperative that shelf life, stability and efficacy are always maintained.  Our product is as safe and effective as the day it was first manufactured.

Chematek customers can use Synhydrid® without any pre-treatment, warming, mixing or any other unnecessary manual handling.

Compare Synhydrid® to LAH

Compare Synhydrid® & DIBAL

Compare Synhydrid® & Sodium Borohydride

HIGHER YIELD

Due to higher concentration with no losses to residues.

DEPOSIT-FREE

No unwanted by-products.

WIDE TEMPERATURE SPECTRUM

Product remains stable from -50C to +170C.

HIGHLY SELECTIVE

No side reactions.

MAXIMISED SAFETY

Non pyrophoric so it’s easy to handle and use. This reduces accidents, safety compliance and handling issues.

EXTREMELY STABLE

Under correct storage conditions the product is ultra-stable over long time periods and temperature extremes. It has a minimum 24 months shelf life.

FLEXIBLE

Can be used across multiple synthesis reactions. This means you only need to hold one reducing agent.

COST SAVING

Less spent on safety and handling of other reducing agents.

Key Reactions

REDUCTION REACTIONS

Synhydrid® performs reduction reactions, transforming functional groups by means of hydride addition. It can reduce esters and acids to alcohols or aldehydes, amides and nitriles to amines, lactones to diols or lactols.

A VERSATILE INITIATOR

Synhydrid® is also a versatile initiator in anionic polymerisation of Caprolactam. It can also be used to initiate Grignard reactions smoothly and effectively.

ESTER

ALCOHOL

ALDEHYDE

ALCOHOL

ACID CHLORIDE

ALCOHOL

KETONE

ALCOHOL

ANHYDRIDE

ALCOHOL

ESTER

ALDEHYDE

NITRILE

ALDEHYDE

ACID CHLORIDE

ALDEHYDE

NITRILE

AMINE

AMIDE

AMINE

IMINE

AMINE

EXPANDING THE POSSIBILITIES

MODIFIED SYNHYDRID®

For increased safety and greater selectivity.

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Synhydrid® APIs

This is just a snapshot of our full API selection. Get in touch today to find out about our full range.

Alongside our current APIs, we’re also working hand-in-hand with customers and partners to expand the Synhydrid® API universe. Visit our Modified Synhydrid® page to find out more and contact us about your requirements and upcoming projects.

EXPLORE APIs

API

APPLICATION

AGOMELATINE

ANTIDEPRESSANT

ALFENTANIL

ANALGESIC

APREPITANT

ANTI VOMITING

ARTENIMOL (DIHYDROARTEMISININ)

ANTI MALARIA

ASENAPINE

ANTIPSYCHOTIC

ATAZANAVIR

ANTIRETROVIRAL

ATOMOXETINE (TOMOXETINE)

ATTENTION DEFICIT HYPERACTIVITY DISORDER

ATORVASTATIN

ANTI CHOLESTEROL

Synhydrid® Applications

POLYMER CHEMICALS

FLAVOUR & FRAGRANCE

LIQUID CRYSTALS

AGROCHEMICALS & PHEROMONES

PHARMA

SPECIALTY CHEMICALS

We are also working with companies on new applications for modified Synhydrid® across a range of new industries.

Can you capitalize on the huge benefits of using Synhydrid® to establish a competitive advantage for your business?

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Eliminate Supply Chain Disruption

Scalable Production Capacity

The world’s largest volume production facility (2000mt per annum), with easily expandable capacity if required.

Multiple Production Sites

Multiple Production Sites

Continuous supply from two co-located sites.

Always Available Stock

Always Available Stock

200mt minimum stock available for delivery at all times.

No Stoppages

No Stoppages

State-of-the-art production facilities ensures no stoppages for regulatory changes and equipment maintenance.

Localised Supply

Localised Supply

Multiple global warehousing to ensure stock is always on-hand.

Cost Efficiency

Cost Efficiency

Supply in local currency for reduced admin resources and cash flow.

Container Management & Packaging Options

Container Disposal

No need to manage container disposal with our returnable container shuttle service.

Custom Quantities

Avoid problems with dosage and residues during production cycles with containers custom filled to exact quantities.

Batch Size Matching

Choice of different size non-returnable packaging for exact batch size matching.

15KG

25KG

50KG

200KG

1000KG

World Class Manufacturing

Synhydrid® is manufactured by Lučební závody a.s. Kolín, a respected chemical manufacturer in the Czech Republic that has been operating for over 150 years. Lučební are the original manufacturers of sodium dihydridobis(2-methoxyethoxo)aluminate and their brand, Synhydrid® has a global reputation for stability and quality. Chematek are proud to represent Lučební as the exclusive global distribution partner for the product.

Reduction Chemistry Experts

Recognizing the potential of Synhydrid® in the early 2000s, Lučební appointed Chematek as their Exclusive Global Distribution Partner.

With supply chain integrity and market development a priority, Chematek were chosen for their expertise in reduction chemistry, worldwide networks and global distribution skills.

Increasing
Demand

Lučební recognise the need for a stable supply line of high quality product and by 2025 will have increased Synhydrid® production capacity to 3000 MT per year. This includes multiple production lines designed to insulate customers from any supply chain disruptions.

WORKING WITH US

THE CHEMATEK DIFFERENCE

EXPERTISE FROM EXPERIENCE

Four Divisions. One Team

Synhydrid® is one of the flagship products from boutique industrial services company Chematek.

Chematek is a boutique industrial services company, operating four distinct but interlinked product divisions: Fine Chemicals, Petro Chemicals, Lubricants and Oil & Gas Engineering, Procurement and Construction.

The specialist services provided by each division are enriched by our diverse, cross divisional knowledge and deep functional expertise. Our diversity gives us unique and transferable insights which enable us to deliver better product solutions for our clients. Our boutique scale means that every client is highly valued and our team of experts are easily accessible.

REACH accreditation

Full technical support

Global logistics network

Demonstrated plant safety

Dedicated R&D team with in-house laboratories

Experienced track record in hard to find, difficult to manage Fine Chemicals

Exclusive R&D partnerships with large clients

Assured systems and handling

Customs and Documentation

Strategic warehouse network

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