SAFE, SECURE & RELIABLE ALTERNATIVES

The Complete Guide to Synhydrid® & Piperhydride®

Discover the potential of Synhydrid® and Piperhydride® as reducing agents in organic synthesis.

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Using detailed comparisons, learn how their properties differ from traditional reducing agents and how they are being used in real-world applications.

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Content Provided

• Synthesis and physicochemical properties of Synhydrid® and Piperhydride®.
• A comparison with other reducing agents (LiAlH₄, NaBH₄).
• The reaction mechanisms for various functional group transformations.
• Applications in the synthesis across various categories including pharmaceuticals (Tolterodine, Sofosbuvir).

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Key Takeaways

A Safer, More Versatile Alternative

Synhydrid® addresses the pyrophoric nature and hazardous handling associated with LiAlH4 and DIBAL-H and overcomes limitations of NaBH4 in reducing a wider range of functional groups.

Targeted Reductions

Synhydrid® provides better control over reduction reactions compared to LiAlH4.

Solve Solubility Constraints

Synhydrid® allows for selective reduction of target functional groups while minimising interference with others.

Partial Reductions

Piperhydride® facilitates selective reductions (esters to aldehydes, lactones to lactols) at lower temperatures

SYNHYDRID® VS SODIUM BOROHYDRIDE

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Find out how Synhydrid® is able to replace other metal hydride agents like Sodium Borohydride with greater safety and more selective reductions.

Take a look at our white paper today for information on handling, storage, and experimental procedures for using Synhydrid® and Piperhydride®.

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